Synthesis of complete systems, application- and domain-specific synthesis techniques; system-level models for design, optimization and synthesis; hardware/software co-design and partitioning issues; hardware/software interface and communication synthesis; interface-based and correct-by construction designs; system-level scheduling techniques; protocol synthesis and optimization; system optimization for all cost functions (timing, electrical, non-functional); multi-objective, classical and nature-inspired optimization techniques for system level design; large-scale and industrial case studies involving full system optimization and synthesis.